Effects of different anti-inflammatory drugs on lipopolysaccharide (LPS) induced vascular cell adhesion molecule 1 (VCAM-1) expression in pancreas, stomach, heart, and skeletal muscle
| LPS | ||||||
|---|---|---|---|---|---|---|
| Treatment | Control | Untreated | 5-ASA | DEX | MTX | 6-MP |
| Pancreas | 66 (4) | 223 (6) | 161 (7)7-150 | 150 (6)7-150 | 169 (5)7-150 | 205 (13) |
| Stomach | 93 (10) | 309 (16) | 256 (13) | 193 (3)7-150 | 255 (14) | 310 (23) |
| Heart | 117 (12) | 761 (41) | 602 (29)7-150 | 584 (37)7-150 | 558 (39)7-150 | 673 (52) |
| Muscle | 34 (3) | 112 (7) | 68 (7)7-150 | 56 (6)7-150 | 90 (6) | 105 (5) |
Results are expressed as mean (SEM) in ng monoclonal antibody/g tissue.
↵7-150 p<0.05 v LPS + untreated.
5-ASA, 5-aminosalicylic acid; DEX, dexamethasone; MTX, methotrexate; 6-MP, 6-mercaptopurine.