Similarities and dissimilarities between primary biliary cirrhosis (PBC) and coeliac disease (see text for references)
| Coeliac disease | PBC | |
|---|---|---|
| Sex distribution (F:M) | 3:2 | 9:1 |
| HLA associations | DR3DQ2; DR5DR7; DR4DQ8 | DR8 |
| Incidence in first degree relatives | 10–20% | 3–4% |
| Disease associations | Dermatitis herpetiformis; diabetes mellitus; Down’s syndrome | Thyroid disease; other autoimmune diseases |
| Seen in children | Yes | No |