Intragastric acidity at submaximal doses of gastrin 17 in H pylori negative and positive subjects before and during omeprazole
| Gastrin 17 infusion rate (pmol/kg/h) | ||||
|---|---|---|---|---|
| 7 | 20 | 60 | 180 | |
| H pylori negative, before omeprazole | 69.7 (25.9–116.0) | 96.7 (46.8–127.8) | 116.7 (57.6–131.6) | 127.0 (80.9–146.0) |
| H pylori positive, before omeprazole | 71.6 (11–71) | 93.4 (18.4–114.9) | 102.4 (45.6–137.4) | 117.5 (58.1–137.0) |
| H pylori negative, during omeprazole | 7.6 (0.0–57.2) | 29.0 (0.0–96.4) | 66.2 (8.0–108.1) | 87.2 (25.7–108.4) |
| H pylori positive, during omeprazole | 0.0 (0.0–28.2)* | 2.4 (0.0–48.0)† | 17.4 (0.0–81.1)‡ | 30.6 (0.0–96.4)§ |
Intragastric acidity expressed as median (range) in mmol/l.
Acidity less in H pylori positive than inH pylori negative subjects at *p<0.02,†p<0.01, ‡p<0.003, §p<0.001.