Table 1

Impact scores and factor loadings of the items from the item reduction step

CLDQ items	Proportion with problem	Importance	Impact	Factor loadings
Factor 1
Decreased strength	0.69	3.95	2.73	0.69
Fatigue	0.80	3.88	3.10	0.82
Decreased level of energy	0.81	4.04	3.27	0.79
Lack of energy	0.59	4.24	2.50	0.75
Feeling weak	0.63	3.88	2.44	0.83
Feeling worn out	0.70	3.89	2.72	0.79
Feeling sleepy during the day	0.80	3.55	2.84	0.53
Tired in the morning when you wake up	0.59	4.03	2.38	0.57
Tired in the afternoon	0.77	3.37	2.59	0.58
Drowsiness	0.63	3.55	2.24	0.61
Problem carrying heavy objects	0.55	3.49	1.92	0.55
Anxiety	0.69	3.73	2.57	0.54
Factor 2
Feeling depressed	0.56	4.00	2.24	0.51
Irritability	0.55	4.03	2.22	0.48
Mood swings	0.52	4.09	2.13	0.51
Difficulty sleeping at night	0.61	3.77	2.30	0.71
Unable to fall asleep at night	0.58	3.73	2.16	0.69
The need to get up at night to urinate	0.63	2.98	1.88	0.40
Not feeling rested in the morning	0.67	3.84	2.57	0.61
Factor 3
Worried about the impact your disease has on your family	0.64	3.90	2.50	0.74
Worried your symptoms will develop into a major problem	0.73	4.02	2.93	0.79
Worried never feeling any better	0.52	4.36	2.27	0.60
Worried condition getting worse	0.83	4.08	3.39	0.81
Factor 4
Feeling bloated	0.66	3.48	2.30	0.80
Abdominal discomfort	0.55	3.43	1.89	0.66
Abdominal bloating	0.58	3.81	2.21	0.83
Muscle cramps at night	0.56	3.58	2.00	0.47
Factor 5
Trouble lifting heavy objects	0.53	3.59	1.90	0.51
Change in eating habits	0.56	3.44	1.93	0.76
Not able to eat as much as before	0.56	2.81	1.57	0.58
Napping during the day	0.61	3.23	1.97	0.56
Factor 6
Shortness of breath	0.53	3.88	2.06	0.49
Dry mouth	0.61	3.33	2.03	0.52
Worried about the availability of a liver if you need a transplant	0.55	4.60	2.53	0.64
Itching	0.53	3.24	1.82	0.40

Proportion of variance explained: factor 1, 0.224; factor 2, 0.122; factor 3, 0.110; factor 4, 0.099; factor 5, 0.098; factor 6, 0.056.