Serum HCV RNA levels at three and 12 months after transplantation for HCV cirrhosis in relation to type of initial immunosuppressive therapy
| Initial immunosuppression | Median (range) HCV RNA (× 106 Eq/ml) | p Value | |||
|---|---|---|---|---|---|
| 3 months | 12 months | ||||
| Triple (n=31) | 4.7 (<0.2–98.0)1 | 10.5 (<0.2–2000.0)4 | 0.08 | ||
| Double (n=5) | 4.4 (<0.2–18.0)2 | 5.0 (0–61.5)5 | 0.89 | ||
| Single (n=11) | 18.0 (8.7–210.0)3 | 4.9 (0.5–12.8)6 | 0.003 | ||
Triple therapy included cyclosporin, azathioprine, and prednisolone; double, cyclosporin and prednisolone; and single, cyclosporin (or tacrolimus in three patients) alone.
1 versus 3, p=0.002; 2 versus 3, p=0.054; 4 versus 5, p=0.51; 5 versus 6, p=0.78, 4 versus 6, p=0.08.