Assessment of the inflammatory response induced by H felis infection
| Strain | Antrum | Body | Functional atrophy | Lymphoid aggregates |
|---|---|---|---|---|
| CBA/Ca | 0.2 (0.4) | 0.3 (0.9) | 0.5 (1.0) | 0.2 (0.6) |
| C3H/He | 0.8 (0.4) | 1.8 (1.2) | 1.1 (1.5) | 0.8 (1.0) |
| C57BL/6 | 0.6 (0.5) | 1.3 (1.0) | 1.0 (1.3) | 1.1 (1.0) |
| SJL | 0.9 (0.7) | 1.8 (1.1) | 0.9 (0.9) | 1.3 (1.0) |
| CBA×C3H/He | 0.4 (0.5) | 0.2 (0.4)2-150 | 02-150 | 02-150 |
| CBA×C57BL/6 | 0.1 (0.3)2-150 | 02-150 | 02-150 | 02-150 |
| SJL×CBA | 0.2 (0.4)2-150 | 0.3 (0.9)2-150 | 02-150 | 0.3 (0.6)2-150 |
Gastric inflammation was assessed by light microscopic examination of H&E stained sections. The values represent the mean (SEM) scores from n=10 mice per group.
↵2-150 Values shown for the F1 hybrid strains were significantly reduced compared with their respective responder strain parent (C3H/He, C57BL/6, SJL; p<0.05) but not significantly different from their non-responder CBA/Ca parent.