Clinical data on patients with intrahepatic cholestasis of pregnancy
| Non-UDCA | UDCA | |
|---|---|---|
| Age (years) | 32.4 (4.2) (26–36) | 30.8 (4.8) (23–35) |
| Recurrence | 0 | 4 |
| Gemelar pregnancy | 1 | 0 |
| Onset of pruritus (weeks) | 33.1 (3.2) (28–35) | 28.7 (4.0) (26–34)1-150 |
| Gestational age at diagnosis (weeks) | 35.4 (1.8) (33–37) | 32.0 (2.1) (29–35)** |
| Gestational age at delivery (weeks) | 36.5 (2.2) (34–39) | 36.7 (0.4) (35–39) |
| Green amniotic fluid | 2 | 3 |
| Newborns | ||
| Birth weight (g) | 2870 (660) (2110–3670) | 2902 (232) (2490–3380) |
| Apgar score | ||
| 1 minute | 8.6 (0.9) | 9.0 (0.0) |
| 5 minutes | 9.8 (0.5) | 10.0 (0.0) |
Patients with intrahepatic cholestasis of pregnancy received classical palliative therapy (non-UDCA group; n = 7) or were treated with ursodeoxycholic acid (UDCA) until labour (UDCA group; n = 9). Values are expressed as mean (SD) (respective range).
↵1-150 p<0.05 and **p<0.01, v non-UDCA.