Effect of lipid on biliary lipid composition
| LCT | MCT/LCT | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Time 0 | End (6 h) | Post (9 h) | Post (24 h) | Time 0 | End (6 h) | Post (9 h) | Post (24 h) | Control | ||||
| CH | 4.1 (1.5) | 4.8 (2.4)5-150 | 3.0 (0.9) | 3.0 (0.7) | 3.6 (1.4) | 5.1 (1.8)5-150 | 4.0 (1.6) | 3.5 (1.4) | 4.2 (0.6) | |||
| PL | 8.8 (3.5) | 10.5 (5.2) | 5.7 (3.2) | 5.6 (2.7) | 9.0 (4.3) | 9.8 (5.5) | 7.3 (5.4) | 7.8 (4.9) | 7.0 (0.9) | |||
| BS | 28.9 (10.8) | 21.1 (12.2) | 22.6 (10.9) | 19.2 (6.7) | 37.8 (16.8) | 25.1 (16.9) | 23.6 (15.3) | 31.2 (11.8) | 28.0 (3.4) | |||
| CH:PL | 0.5 (0.2) | 0.6 (0.2) | 0.5 (0.2) | 0.6 (0.3) | 0.4 (0.1) | 0.5 (0.1) | 0.6 (0.2) | 0.5 (0.2) | 0.6 (0.1) | |||
| Total lipids | 23 (8) | 19 (6)† | 19 (11) | 15 (5) | 26 (12) | 16 (10)† | 9 (12) | 22 (10) | 21 (1) | |||
| CSI | 2.5 (2.0) | 3.4 (1.5) | 3.2 (1.8) | 2.6 (1.1) | 1.8 (0.6) | 3.9 (1.8)** | 2.9 (1.4) | 1.3 (0.8) | 2.4 (0.4) | |||
| Bile flow | 0.5 (0.2) | 0.5 (0.2) | 0.4 (0.2) | 0.4 (0.1) | 0.5 (0.2) | 0.4 (0.0) | 0.4 (0.1) | 0.3 (0.1) | 0.4 (0.1) | |||
Results are expressed as mean (SD). Control values represent means of three time points.
↵5-150 p<0.05, **p<0.01, †p<0.005 compared with time 0.
CH, total (free) cholesterol; PL, phospholipids; BS, bile salts; CSI, cholesterol saturation index.
CH, PL, and BS are expressed in mM, total lipids in g/l, bile flow in ml/min.