No (%) of patients with flare up | Median time to flare up (days) | p Value (log rank test) | |
---|---|---|---|
Total | 146/328 (45) | 504 (49) | |
Recently active disease | |||
Yes | 107/180 (59) | 337 (7) | < 0.0001 |
No | 39/148 (26) | > 614 | |
CDAI | |||
>150 | 36/49 (73) | 263 (89) | < 0.0001 |
<151 | 110/279 (39) | 548 (18) | |
Colonic lesions | |||
Yes | 91/169 (54) | 405 (26) | 0.0004 |
No | 55/159 (35) | > 614 | |
Anoperineal lesions | |||
Yes | 41/68 (60) | 266 (62) | < 0.0001 |
No | 105/260 (40) | 535 (14) | |
Steroid therapy | |||
Yes | 65/100 (65) | 355 (8) | < 0.0001 |
No | 81/228 (35) | > 614 | |
Current smoking | |||
Yes | 97/183 (53) | 444 (29) | 0.002 |
No | 49/145 (34) | > 581 |
Results for time to flare up are expressed as median (SD).
Note: The following were not significant: age, duration of disease, small bowel lesions, previous intestinal resection, 5-aminosalicylate treatment, immunosuppressive therapy, use of oral contraceptives.
CDAI, Crohn’s disease activity index.