Affected sib pairs | ||||
---|---|---|---|---|
Number of haplotypes shared | 0 | 1 | 2 | Total |
Observed number of sib pairs | 4 | 30 | 18 | 52 |
Expected number of sib pairs | 13 | 26 | 13 | 52 |
χ2=8.769, df=2, p=0.013 (for sharing zero, one, and two) | ||||
χ2=8.308, df=1, p=0.004 (for sharing zerov sharing at least one) | ||||
Affected sib trios | ||||
Number of haplotypes shared by all three affected sibs | 0 | 1 | 2 | Total |
Observed number of sib trios | 2 | 3 | 2 | 7 |
Expected number of sib trios | 3.94 | 2.63 | 0.44 | 7 |