Predictive factors of sustained virological response to interferon (univariate analysis)
| Patients with and without cryoglobulins (n=87) | Patients with cryoglobulins (n=43) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Sustained VR (n=15) | p | OR | CI | Sustained VR (n=7) | p | OR | CI | ||
| Age (years) | 52 (16) | 0.5 | — | — | 56 (15) | 0.8 | — | — | |
| Sex (% M) | 87 | 0.008 | 5.53 | 1.7–19 | 86 | 0.032 | 7.57 | 1–40 | |
| Cirrhosis (%) | 13 | 0.12 | — | — | 14 | 0.21 | — | — | |
| Duration of LD (years) | 11 (8) | 0.25 | — | — | 10 (7) | 0.07 | — | — | |
| Presence of Cgs (%) | 47 | 0.81 | — | — | — | — | — | — | |
| Cryoglobulin concentration before IFN (g/1) | 0.30 (0.23) | 0.78 | — | — | 0.30 (0.23) | 0.78 | — | — | |
| Viral load (×105 eq/ml) | 21 (30) | 0.022 | — | — | 31 (35) | 0.9 | — | — | |
| Genotype 2 or 3 (%) | 93 | 0.001 | 24 | 7–85 | 83 | 0.008 | 10.8 | 2–53 | |
Where applicable, values are expressed as mean (SD).
VR, virological responder; OR, odds ratio; CI, confidence interval; LD, liver disease; IFN, interferon.