Effect of simvastin and UDCA on serum lipids and the atherogenic index
| Enrolment | Lead in 1 month | Lead in 2 months | Lead in 3 months | Simvastatin | UDCA | Simvastatin + UDCA | |
|---|---|---|---|---|---|---|---|
| Cholesterol (mg/dl) | 303 (12) | 303 (13) | 310 (10) | 308 (12) | 237 (16)1-150 | 297 (12) | 253 (14)1-150 |
| LDL:HDL ratio | 3.7 (0.3) | 2.2 (0.3)‡ | 3.0 (0.3) | 2.3 (0.3)‡ | |||
| Triglycerides (mg/dl) | 219 (54) | 207 (34) | 197 (24) | 201 (28) | 149 (30)§ | 216 (35) | 174 (24) |
| Apolipoprotein A-I (mg/dl) | 155 (7) | 157 (10) | 169 (7) | 154 (11) | |||
| Apolipoprotein B (mg/dl) | 165 (15) | 125 (16)† | 151 (11) | 126 (16)† |
Results expressed as mean (SEM).
↵1-150 p<0.0001, †p<0.002, ‡p<0.003, §p<0.03 compared with pretreatment.