Table 1

Gall bladder motility in 20 control subjects and 16 patients with slow transit constipation (STC)

ControlsSTCSignificance
Fasting gall bladder volume (cm3)23.8  (1.5)17.2  (1.7)p<0.01
Modified sham feeding
 Gall bladder emptying at 30 min (cm3)4.9 (0.7)2.1 (0.7)p<0.02
 Gall bladder emptying at 30 min (%) 21.7 (3.0)11.1 (4.9)p<0.05
Cholecystokinin
 Gall bladder emptying after 60 min (cm3)15.3 (1.4)10.7 (1.1)p<0.05
 Gall bladder emptying after 60 min (%) 67.3 (3.5)72.6 (4.4)NS
 Residual volume (cm3)7.5 (1.0)3.5 (0.4)p<0.01
  • Results are expressed as mean (SEM).