Characteristic | Full responders (n=23) | Incomplete responders (n=47) | p Value |
Cholestasis | |||
Alkaline phosphatase (U/l) | 382 (221), 148–1220 | 813 (455), 199–1933 | p<0.001 |
γ glutamyl transpeptidase (U/l) | 208 (199), 21–948 | 324 (274), 53–1260 | p<0.03 |
Bilirubin (mg/l) | 15 (40), 4–200 | 11 (17), 4–120 | p=0.2 |
Inflammation | |||
Glutamate dehydrogenase (U/l) | 20 (14), 3–56 | 25 (15), 5–63 | p<0.05 |
Alanine aminotransferase (U/l) | 80 (130), 16–560 | 76 (51), 19–210 | p<0.02 |
Aspartate aminotransferase (U/l) | 54 (99), 9–480 | 47 (28), 15–123 | p<0.02 |
Results expressed as mean (SD), range.
Normal reference ranges: <190 U/l for alkaline phosphatase; 4–28 U/l for γ glutamyl transpeptidase; <20 mg/l for bilirubin; <4.5 U/l for glutamate dehydrogenase; 4–22 U/l for alanine aminotransferase; 6–18 U/l for aspartate aminotransferase; 600–2800 mg/l for IgM; and 8000–18000 mg/l for IgG.