Demographic and clinical features at entry
| SMS + Is-5-Mn (n=30) | SMS + placebo (n=30) | Statistical analysis | |
| Age (years) | 64 (8) | 60 (10) | NS |
| Sex (M/F) | 20/10 | 23/7 | NS |
| Aetiology of liver disease | |||
| Alcohol | 13 | 11 | NS |
| HCV | 10 | 13 | NS |
| Alcohol + HCV | 5 | 3 | NS |
| Hepatocarcinoma1-150 | 3 | 1 | NS |
| Child class (AB/C) | 24/6 | 28/2 | NS |
| Score | 7(1) | 7 (1) | NS |
| Clinical features | |||
| Haematemesis | 21 | 25 | NS |
| Time of bleeding until assistance (hours) | 16 (14) | 13 (13) | NS |
| Mean arterial pressure (mm Hg) | 75 (25) | 85 (16) | NS |
| Systolic arterial pressure (mm Hg) | 110 (25) | 118 (24) | NS |
| Diastolic arterial pressure (mm Hg) | 57.5 (25) | 69 (12) | NS |
| Heart rate (bpm) | 92 (26) | 88 (23) | NS |
Values are mean (SD).
↵1-150 Incidental hepatocarcinoma detected during study of liver disease after randomisation.
SMS, somatostatin; Is-5-Mn, isosorbide 5-mononitrate; HCV, hepatitis C virus.