Side effects and complications occurring in the first week after gastrointestinal bleeding
|
Side effects and complications (acute phase) | SMS + Is-5-Mn | SMS + placebo | Statistical analysis |
| Hepatic encephalopathy | 6/30 (20) | 5/30 (17) | NS |
| Pneumonia | 2/30 (7) | 0 | NS |
| Urinary tract infection | 0 | 0 | NS |
| Spontaneous bacterial peritonitis | 3/30 (10) | 0 | NS |
| Bacteraemia | 1/30 (3) | 1/30 (3) | NS |
| Infectious side effects (total) | 6/30 (20) | 1/30 (3) | NS |
| Hepatorenal syndrome | 2/30 (7) | 0 | NS |
| Withdrawal syndrome | 2/30 (7) | 1/30 (3) | NS |
| Headache | 6/30 (20) | 3/30 (10) | NS |
| Hypotension | 5/30 (17) | 3/30 (10) | NS |
| Ascites | 5/30 (17) | 0 | NS (p=0.052) |
| Oligoanuria | 2/30 (7) | 0 | NS |
| Respiratory distress | 1/30 (3) | 0 | NS |
| Atrial fibrillation | 1/30 (3) | 0 | NS |
Values are number (%).
SMS, somatostatin; Is-5-Mn, isosorbide 5-mononitrate.