Relative potency of agonists and antagonists to Y receptors15 16
| Receptor | Agonists | Antagonist |
| Y1 | PYY⩾NPY⩾[Leu31,Pro34]NPY>>PP | BIBP 3226 |
| Y2 | NPY=PYY⩾NPY(13–36)>>PP | |
| Y3 | NPY>>PYY=PP | |
| Y4 | PP>[Leu31,Pro34]NPY>PYY=NPY | |
| Y5 | NPY=PYY=[Leu31,Pro34]NPY⩾NPY(13–36) |
PYY, peptide YY; NPY, neuropeptide Y; PP, pancreatic polypeptide.