Antagonist | PYY induced contraction after pretreatment with the antagonist (%) | p Value versus no pretreatment |
Tetrodotoxin 10−6 M | 65.3 (13.3) | 0.046 |
Hexamethonium 3 × 10−4 M | 66.8 (6.4) | 0.047 |
Atropine 10−6 M | 87.5 (4.2) | 0.1511 |
SR 140333 3 × 10−7 M | 65.9 (3.0) | 0.0156 |
SR 48968 3 × 10−6 M | 100 (0) | NS |
BIBP 3226 10−5M | 100 (0) | NS |
Methiotepin 10−6 M | 100 (0) | NS |
D-600 10−5 M | 0 (0) | 0.001 |
Results are expressed as a percentage of 10−6 M PYY induced contraction and are mean (SD).