Effect of intravenous pretreatment with igmesine on cholera toxin induced jejunal net secretion of electrolytes
| Igmesine (mg/kg) | Net Cl− flux (μmol/min/g) | Net Na+ flux (μmol/min/g) | Net K+ flux (μmol/min/g) | Number |
|---|---|---|---|---|
| 0.00 | −24 (−29 to −17) | −27 (−33 to −18) | −2.0 (−2.0 to −1.4) | 29 |
| 0.03 | −19 (−21 to −17) | −24 (−31 to −17) | −1.7 (−1.7 to −1.5) | 5 |
| 0.10 | −171-150 (−23 to −11) | −171-150(−27 to −13) | −1.51-150 (−2.0 to −1.2) | 19 |
| 0.30 | −181-150 (−20 to −15) | −141-150 (−16 to −13) | −1.5 (−1.7 to −1.4) | 9 |
| 1.00 | −181-150(−20 to 12) | −121-150 (−19 to −10) | −1.41-150 (−1.6 to −1.1) | 10 |
| 3.00 | −161-150 (−16 to −14) | −131-150(−17 to −8) | −0.91-150 (−1.0 to −0.6) | 8 |
| 10.00 | −111-150 (−13 to −9) | −161-150 (−17 to −16) | −1.31-150 (−1.5 to −1.0) | 8 |
Data expressed as median (interquartile range).
↵1-150 p<0.05 compared with cholera toxin (Kruskal-Wallis test).