Table 3

Mucosal fatty acid profile (%) in rats fed the n3 diet at weeks 12 and 19 after the first dose of carcinogen or vehicle

n3 dietWeek 12Week 19
ControlsAOMp ValueControlsAOMp Value
SFAs38.3  (1.27)36.9  (1.21)0.4831.9  (1.93)3-150 32.7  (3.2)0.25
MUFAs35.9 (3.10)37.8 (1.43)0.6031.8 (1.04)32.2 (1.84)3-151 0.86
 C18:1n923.9 (2.20)25.5 (1.19)0.5719.5 (3.03)16.8 (3.9)3-151 0.58
n3 PUFAs10.8 (2.20)9.8 (1.07)0.6715.4 (1.07)13.6 (1.6)0.36
 C18:3n30.12 (0.02)0.13 (0.01)0.950.88 (0.73)1.64 (0.92)0.53
 C20:5n35.76 (1.27)5.46 (0.74)0.848.3 (0.95)5.4 (0.61)0.024
 C22:6n33.48 (0.76)2.88 (0.30)0.484.17 (0.26)3.9 (0.26)3-151 0.50
n6 PUFAs14.9 (1.81)15.4 (1.51)0.8320.8 (2.27)21.5 (3.35)0.87
 C18:2n67.08 (0.46)7.22 (0.31)0.827.65 (0.69)7.01 (0.81)0.57
 C20:3n61.22 (0.23)1.48 (0.24)0.461.83 (0.55)2.32 (0.70)0.59
 C20:4n65.33 (1.00)5.39 (0.85)0.966.92 (0.56)5.2 (0.59)0.053
ARA:EPA1.00 (0.10)0.97 (0.06)0.780.86 (0.07)0.96 (0.06)0.63
  • Values are expressed as mean (SEM).

  • 3-150 p<0.05 v controls at week 12.

  • 3-151 p<0.05 v AOM at week 12.

  • AOM, azoxymethane; SFA, saturated fatty acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid; ARA:EPA, arachidonic acid to eicosapentanoic acid ratio.