Table 4

Mucosal fatty acid profile (%) in rats fed the n6 diet at weeks 12 and 19 after the first dose of carcinogen or vehicle

n6 diet		Week 12					Week 19
n6 diet		Controls	AOM	p Value			Controls	AOM	p Value
SFAs	34.3 (0.30)	35.8 (0.49)	0.022		33.7 (0.50)	35.5 (0.44)	0.025
MUFAs	23.9 (0.22)	22.8 (0.62)	0.12		25.8 (1.07)	24.3 (0.74)	0.52
C_18:1n9	16.9 (0.21)	15.8 (0.46)	0.06		19.8 (0.87)4-150	18.4 (0.77)4-151	0.42
n3 PUFAs	0.63 (0.03)	0.62 (0.04)	0.93		0.81 (0.07)4-150	0.65 (0.03)	0.08
C_18:3n3	0.08 (0.01)	0.08 (0.01)	0.82		0.10 (0.01)	0.07 (0.01)	0.08
C_20:5n3	0.11 (0.003)	0.12 (0.02)	0.37		0.11 (0.01)	0.11 (0.01)	0.81
C_22:6n3	0.39 (0.02)	0.37 (0.02)	0.49		0.46 (0.06)	0.38 (0.02)	0.11
n6 PUFAs	41.1 (0.44)	40.6 (0.91)	0.61		39.6 (0.63)	39.5 (0.45)	0.87
C_18:2n6	16.1 (0.48)	16.7 (1.20)	0.64		19.5 (1.06)4-150	18.02 (1.25)	0.20
C_20:3n6	2.42 (0.15)	2.84 (0.15)	0.08		1.70 (0.20)4-150	1.88 (0.12)^††	0.42
C_20:4n6	19.9 (0.56)	18.4 (0.26)	0.051		15.8 (1.00)^**	16.9 (1.19)	0.26
ARA:EPA	189.2 (8.8)	161.6 (23.2)	0.26		146.4 (11.4)4-150	152.2 (9.1)	0.99

Values are expressed as mean (SEM).
↵4-150 p<0.05 and ^**p<0.01 v controls at week 12.
↵4-151 p<0.05 and ^††p<0.01 v AOM at week 12.
AOM, azoxymethane; SFA, saturated fatty acid; MUFA, monounsaturated fatty acid; PUFA, polyunsaturated fatty acid; ARA:EPA, arachidonic acid to eicosapentanoic acid ratio.