Table 2

Molecular and immunohistochemical features of 159 patients with T3,N0,M0 colorectal cancer stratified by replication error (RER) status

RER− cancers (n=137) RER+ cancers (n=22) OR (95% CI) p Value
K-ras mutation2-150
Absent90 (69%)19 (86%)0.40 (0.08–1.37)0.132-151
 Present40 (31%)3 (14%)
p53 immunostaining
Absent77 (56%)10 (46%)1.52 (0.57–4.17)0.482-152
 Present60 (44%)12 (55%)
c-erbB-2 immunostaining2-150
Absent85 (66%)9 (45%)2.38 (0.85–6.95)0.112-152
 Present43 (34%)11 (55%)
c-myc immunostaining2-150
Absent53 (42%)6 (30%)1.60 (0.19–1.81)0.462-152
 Present74 (58%)14 (70%)
  • 2-150 Information not available for all patients.

  • 2-151 Fisher's exact test.

  • 2-152 χ2 test.

  • OR, odds ratio; CI, confidence interval.