Risk factors of fulminant hepatic failure in acute hepatitis C
| Risk factors | Fulminant (n = 11) | Non-fulminant (n = 98) | Odds ratio (95% CI) |
|---|---|---|---|
| Age | |||
| ⩽40 y | 36 | 34 | 1.00 |
| >40 y | 64 | 66 | 0.89 (0.25 to 3.19)2-150 |
| Sex | |||
| Male | 73 | 60 | 1.00 |
| Female | 27 | 40 | 0.57 (0.14 to 2.24)2-150 |
| HCV genotype | |||
| 1b | 82 | 86 | 1.00 |
| 1b+2a or 1b+2b | 18 | 9 | 2.07 (0.40 to 10.72)2-150 |
| Not classified | 0 | 5 | 0.81 (0.46 to 1.42)2-150 |
| Serum levels of HCV RNA | |||
| <105 copies/ml | 73 | 70 | 1.00 |
| 105–107 copies/ml | 27 | 23 | 1.18 (0.28 to 4.96)2-150 |
| >107 copies/ml | 0 | 7 | 0.55 (0.15 to 2.02)2-150 |
| Concurrent HGV infection | |||
| Negative | 91 | 89 | 1.00 |
| Positive | 9 | 11 | 0.79 (0.09 to 6.84)2-150 |
| Concurrent HBV infection | |||
| Negative | 18 | 69 | 1.00 |
| Positive | 82 | 31 | 10.20 (4.74 to 21.95)† |
Results are expressed as percentages.
↵2-150 p>0.2, †p<0.01 by the χ2 test with Yates’ correction.
HCV, hepatitis C virus; HBV, hepatitis B virus; HGV, hepatitis G virus.