Table 4

Correlation coefficients and p values of significance for the relationship between rectal mucosal release of cytokines and eicosanoids measured with the filter paper technique, and sigmoidoscopic,24 clinical activity,25 and histological26 scores in patients with ulcerative colitis

Score Mediator n Correlation
coefficient (r)
p Value
Sigmoidoscopic score
IL-1β25+0.710.0001
TNF-α12+0.760.005
TXB2 31+0.80<0.0001
PGE2 25+0.75<0.0001
Clinical activity score
IL-1β25+0.430.0007
TNF-α12+0.890.02
TXB2 31+0.69<0.0001
PGE2 25+0.510.009
Histological score
IL-1β17+0.760.04
TNF-α10+0.71<0.0001
TXB2 16+0.87<0.0001
PGE2 16+0.640.01