Table 5

Weight of fluid collected on the filter paper and the corrected IL-1β, TNFα, and eicosanoid levels (for weight) for patients with active and inactive ulcerative colitis(defined by sigmoidoscopic score) and in controls. Median (IQR) are shown

Ulcerative colitisControlsn
ActivenInactiven
Weight of mucosal fluid (mg)42.7  (31.2–57.3)1018.5  (14.4–24.1)5-150 1219.3  (16.5–23.8)5-150 8
Corrected cytokine/eicosanoid level
 IL-1β (pg/ml mucosal fluid)57.9 (28.4–121)61.5 (0.8–2.7)** 61.3 (0.9–4.7)5-150 5
 TNF-α (pg/ml mucosal fluid)8.4 (3.2–11.9)60.68 (0.34–3.5)** 60.36 (0.28–0.81)** 5
 TXB2 (pg/ml mucosal fluid)192 (123–249)622.9 (8.6–37.8)5-150 610.6 (8.8–14.8)5-150 4
 PGE2 (pg/ml mucosal fluid)1574 (869–2184)588.8 (53.4–263)** 4102 (49–310)** 4
  • 5-150 p<0.0001, **p=0.02 compared with active UC