Table 2

Histological scores for wild type and inducible nitric oxide synthase (iNOS) deficient mice, 24 and 72 hours, and seven days after administration of trinitrobenzene sulphonic acid (TNBS)

Time pointWild typeiNOS deficient
Untreated0.3 (0.2)0.2 (0.2)
TNBS—24 h7.5 (0.2)* 8.0 (0)*
TNBS—72 h4.8 (1.0)* 5.1 (0.7)*
TNBS—7 days6.4 (1.0)* 7.9 (1.0)*
  • n⩾5. *Significant increase from untreated groups. No significant differences in histological scores were observed between the two groups.