Baseline model | Sensitivity analysis | |
Sensitivity in detecting dysplasia and CRC | 90% | 50–100% |
Specificity of surveillance in detecting dysplasia and CRC | 95% | 80–100% |
Case fatality rate of CRC in surveillance | 13% | 5–45% |
Health related quality of life after proctocolectomy | 95% | 85–100% |
Surveillance interval | 2 y | 1–5 y |
Time lag between dysplasia and CRC | 3 y | 1–5 y |
Costs per surveillance colonoscopy | $911 | $200–$1500 |
Costs of proctocolectomy | $8300 | $4150–$16 600 |
Costs of terminal care per patient with CRC | $34 100 | $17 050–$68 200 |
Average annual income | $24 294 | $10 000–$50 000 |
Annual discount rate | 3% | – |
CRC, colorectal cancer.