Table 1

Effect of orlistat on gastric emptying of the solid and fat meal phases

Solid phaseFat phase
PlaceboOrlistatPlaceboOrlistat
Lag period (minutes)57 (11)34 (6)33 (5)22 (1)*
t½ (minutes)363 (89)175 (19)** 255 (42)144 (15)***
AUC (% counts×min)14 542 (434)12 842 (456)** 13 522 (441)11 799 (299)***
  • Values are mean (SEM). *p<0.05, **p<0.03, ***p<0.02 orlistatv placebo.