Peak serum concentrations of various mediators in severe versus mild acute pancreatitis (AP) (median (interquartile range))
| IL-1β (pg/ml) | IL-1RA (U/ml) | sIL-2R (pg/ml) | IL-6 (ng/ml) | IL-8 (pg/ml) | IL-10 (U/ml) | |
|---|---|---|---|---|---|---|
| Severe AP (n= 35) | 5.1 (3.6–8.2) | 4759 (3451–7000) | 996 (574–2582) | 722 (347–1680) | 100 (73–158) | 13.6 (11–55) |
| Mild AP (n=16) | 2.87 (0.1–4.4) | 1796 (1515–2425) | 568 (373–819) | 268 (107–443) | 110 (59–678) | 2.8 (0.2–4.9) |
| p Value | 0.05 | 0.01 | 0.005 | 0.006 | NS | 0.01 |
IL, interleukin; IL-1RA, interleukin 1β receptor antagonist; sIL-2R, soluble interleukin 2 receptor.