Serological, histological, and HLA typing of the family studied
| Subject No | Relationship | Age (y) | HLA-A | HLA-B | HBV status | ALT (iu/l) | HBV DNA |
| 8 | Father | 53 | 11, 11 | 7, 15 | HBsAg neg | 36 | Neg |
| 9 | Mother | 49 | 68, 68 | 51, 50 | HBsAg/anti-HBe pos | 22 | Neg |
| 10 | Daughter | 28 | 11, 68 | 5, 7 | HBsAg/anti-HBe pos | 22 | Neg |
| 11 | Daughter | 27 | 11, 68 | 7, 50 | HBsAg/anti-HBe pos | 17 | Neg |
| 12 | Daughter | 26 | 11, 68 | 15, 50 | HBsAg/HBeAg pos | 45 | >16 000 pg/ml |
| 13 | Daughter | 24 | 11, 68 | 15, 51 | HBsAg/anti-HBe pos | 20 | Neg |
| 14 | Daughter | 22 | 11, 68 | 7, 51 | HBsAg neg | 11 | Neg |
Serum alanine transaminase (ALT, normal range 5–40 iu/l) and serum hepatitis B virus (HBV) DNA measurements (branched chain DNA assay; Chiron Corporation, Emeryville, California, USA) are shown. Liver biopsy findings are shown where performed (nd indicates liver biopsy not performed).
HBV, hepatitis B virus; HBe, hepatitis B e; HBeAg, hepatitis B e antigen; HBsAg, hepatitis B surface antigen; pos, positive; Neg, negative.