Botx 50 U (n=40) | Botx 100 U (n=38) | Botx 200 U (n=40) | p Value | |
At 30 days | ||||
LES basal pressure (mm Hg) | 24.3 (13) | 24.2 (10.4) | 21 (7.3) | NS |
Symptom score | 1.7 (1.9) | 1.5 (1.8) | 1 (1.2) | NS |
Chest pain after injection | 3/40 | 2/38 | 4/40 | NS |
Failures | 10/40 | 6/38 | 5/40 | NS |
50 U (n=30) | 100 U×2 (n=32) |
200 U (n=35) | ||
At the end of follow up | ||||
Relapses | 14/30 | 6/32 | 15/35 | 0.04 |
Duration of follow-up (months) | 11.9 (6) | 12.8 (5) | 9.7 (4.7) | NS |
Cumulative months of remission | 246 | 371 | 206 | 0.01 |