Clinical details of C282Y homozygotes (all males)
| Patient; age | Reason for LFTs request | Clinical conditions | Family history (1st degree relatives) | Alcohol intake (units/week) | Units of blood venesected) (iron removed (g))2-150 |
|---|---|---|---|---|---|
| A; 49 y | Routine test from diabetic clinic | IDDM | No siblings | 84 | 26 (6.5) |
| B; 70 y | Hypertensive routine test (GP) | IHD, hypertension | 1 sister C282Y +/+ | 0 | 8 (2) |
| C; 50 y | Routine test (GP) | Depression | No iron overload detected in siblings | 20 | |
| D; 44 y | Routine test (GP) | Backache, arthritis | No siblings | 2 | 11 (2.75) |
| E; 48 y | Routine test (GP) | Knee replacement | No iron overload detected in siblings | 48 | 16 (4.0) |
| F; 54 y | Tired routine test (GP) | IDDM | 1 cousin C282Y +/+, no siblings | 50 | 44 (11g) |
| G; 61 y | Routine test (GP) | Fit | No iron overload detected in siblings | 8 | 23 (5.75) |
| H; 51 y | Routine test (GP) | Arthritis, alcohol excess | 154 | 14 (3.5) |
↵2-150 Assuming 1 unit (500 ml) of blood contains 250 mg of iron.
LFTs, liver function tests; IHD, ischaemic heart disease; IDDM, insulin dependent diabetes mellitus.