| Non-responders (n=21) | Responders (n=97) | p Value |
Sex (M/F) | 12/9 | 50/47 | NS |
Mean age (years) | 49.3 (19) | 57.5 (18) | 0.03 |
Symptom duration (months) | 48 (60) | 45.5 (54) | NS |
Previous dilatation/myotomy | 3/21 | 6/97 | NS |
Vigorous achalasia | 5/21 | 31/97 | NS |
Weight loss (kg) | 3 (3.9) | 3.9 (4.3) | NS |
Oesophageal diameter (cm) | 4.5 (1.2) | 4 (1) | NS |
Pretreatment LES (mm Hg) | 39.7 (15) | 33.3 (10) | NS |
Pretreatment symptom score | 5.9 (1.2) | 5.2 (1.6) | NS |
At 30 days | | | |
Post-treatment LES (mm Hg) | 36.6 (13) | 20.5 (7.6) | 0.001 |
Post-treatment symptom score | 4.4 (1.6) | 0.8 (0.6) | 0.001 |
Chest pain after injection | 2 | 7 | NS |