Effect of neural blockade on IL-8 stimulated 3-O-methyl glucose transport
| Jms (μEq/cm2/h) | Jsm (μEq/cm2/h) | Jnet (μEq/cm2/h) | PD (mV) | Isc (μA/cm2) | G (mS/cm2) | |
|---|---|---|---|---|---|---|
| Basal | 0.83 (0.12) | 0.24 (0.03) | 0.59 (0.12) | 2.7 (0.2) | 30 (2) | 28 (2) |
| IL-8 (100 ng/ml) | 1.25 (0.13)3-a | 0.25 (0.04) | 0.99 (0.14)3-a | 2.2 (0.2)3-b | 24 (1)3-b | 27 (2) |
| (n=5) | Δ=0.42 (0.12) | Δ=0.01 (0.04) | Δ=0.40 (0.15) |
Data are mean (SEM).
Jms, mucosal to serosal flux; Jsm, serosal to mucosal flux; Jnet, net flux; PD, potential difference; Isc, short circuit current; G, conductance.
↵3-a p<0.05,
↵3-b p<0.01 compared with basal period.
TTX 5×10-7 M was added to the serosal reservoir of all chambers immediately after mounting of the tissue.