Table 4

Effect of IL-1α and IL-8 on jejunal proline transport

Jms
(μEq/cm2/h)		Jsm
(μEq/cm2/h)		Jnet
(μEq/cm2/h)		PD
(mV)		Isc
(μA/cm2)		G
(mS/cm2)
Basal0.76 (0.11)0.15 (0.01)0.61 (0.1)2.5 (0.3)28 (5)27 (3)
IL-1α (5 ng/ml)0.80 (0.13)0.17 (0.01)0.63 (0.13)2.5 (0.3)27 (4)26 (3)
 (n=4)Δ=0.04 (0.02)Δ=0.02 (0.01)Δ=0.02 (0.03)
Basal0.60 (0.05)0.28 (0.04)0.32 (0.05)3.0 (0.1)37 (2)32 (2)
IL-1α (50 ng/ml)0.69 (0.07)4-a 0.30 (0.04)0.38 (0.05)4-a 2.7 (0.1)4-a 32 (1)4-b 30 (2)
 (n=5)Δ=0.09 (0.03)Δ=0.02 (0.01)Δ=0.07 (0.02)
Basal0.77 (0.07)0.23 (0.02)0.54 (0.05)2.5 (0.1)31 (3)31 (2)
IL-8 (100 ng/ml)0.85 (0.07)4-b 0.26 (0.02)4-a 0.59 (0.06)4-a 2.4 (0.1)29 (3)30 (2)4-a
 (n=6)Δ=0.07 (0.01)Δ=0.03 (0.01)Δ=0.05 (0.02)

  • Data are mean (SEM).

  • Jms, mucosal to serosal flux; Jsm, serosal to mucosal flux; Jnet, net flux; PD, potential difference; Isc, short circuit current; G, conductance.

  • ↵4-a p<0.05,

  • ↵4-b p<0.01 compared with basal period.