Association between body mass index (BMI)3-150 levels at three different time points in life and severity of reflux symptoms3-151 analysed in continuous form among 135 individuals with reflux symptoms
| Age and sex adjusted | Multivariately3-152 adjusted | ||||||
|---|---|---|---|---|---|---|---|
| β | SE (β) | p | β | SE (β) | p | ||
| Maximum adult BMI | |||||||
| BMI <25 | 0.0 (reference) | 0.0 (reference) | |||||
| BMI 25–30 (overweight) | −0.06 | 0.10 | 0.58 | −0.06 | 0.11 | 0.56 | |
| BMI >30 (obesity) | −0.03 | 0.14 | 0.84 | −0.02 | 0.15 | 0.90 | |
| BMI 20 years before interview | |||||||
| BMI <25 | 0.0 (reference) | 0.0 (reference) | |||||
| BMI ⩾25 (overweight or obesity) | −0.05 | 0.10 | 0.62 | −0.05 | 0.11 | 0.65 | |
| BMI at age 20 | |||||||
| BMI <25 | 0.0 (reference) | 0.0 (reference) | |||||
| BMI ⩾25 (overweight or obesity) | −0.27 | 0.15 | 0.07 | −0.27 | 0.15 | 0.07 | |
↵3-150 Body mass index was calculated as body weight divided by the square of body height in metres (kg/m2).
↵3-151 Severity of gastro-oesophageal reflux was defined according to a reflux score The score included symptom characteristics (heartburn only, 1 point; regurgitation only, 1 point; heartburn and regurgitation combined, 1.5 points), nightly symptoms (yes, 2 points), and symptom frequency (once a week, 0 points; 2–6 times/week, 1 point; 7–16 times/week, 2 points; >16 times/week, 3 points).
↵3-152 Adjustments were made for age, sex, tobacco smoking, alcohol use, meal sizes, and physical activity.