Table 2

Time/activity curve parameters for99mTc-DISIDA biliary scanning with and without morphine provocation in patients with normal (group I) and elevated (>40 mm Hg) (group II) sphincter of Oddi basal pressure

Group IGroup IIp Value
n1618
Without morphine provocation
 Tmax (minutes)16 (12–29)22 (10–63)0.07
 E45 (%)37.2 (10.2–58.4)26.7 (0–62.3)0.2
 E60 (%)55.5 (30.1–70.5)38.8 (0–74.5)0.1
With morphine provocation
 Tmax (minutes)30.5 (18–49)39.5 (23–70)0.03
 E45 (%)9.5 (0–24.9)1.8 (0–33.7)0.04
 E60 (%)28.2 (3.5–43.6)4.9 (0–51.6)0.002
  • Values are median (range).

  • Tmax refers to time to maximal activity and E45 and E60 refer to the percentage of maximal activity cleared (emptied) from the biliary system at 45 and 60 minutes, respectively.