Age at onset of Crohn's disease stratified by ANCA and ASCA expression
| Pre-teenage onset CD (<13 y) (range 4–12 y) (n=22) | Teenage and young adult onset CD (range 13–40 y) (n=110) | Late adult onset CD (>40) (range 42–67 y) (n=24) | p Value | |
|---|---|---|---|---|
| ASCA+ | 16 (73%) | 65 (59%) | 7 (29%) | 0.003 |
| IgG and IgA ASCA+ | 11 (50%) | 43 (39%) | 4 (17%) | 0.02 |
| ANCA+ | 12 (55%) | 58 (53%) | 17 (71%) | NS |
| pANCA+ | 4 (18%) | 23 (21%) | 6 (25%) | NS |
Statistical differences in proportions were evaluated using the χ2 test for trend.
ASCA, anti-Saccharomyces cerevisiae antibody; ANCA, antineutrophil cytoplasmic antibodies; CD, Crohn's disease.