Table 1

Clinicopathological features of microsatellite instability-high (MSI-H), microsatellite instability-low (MSI-L), and microsatellite stable (MSS) colorectal cancers

Variables	Total	MSI-H (n=32)	MSI-L (n=30)	MSS (n=40)	p Value
Age (mean (SD)		72.6 (6.1)	69.0 (10.9)	67.9 (12.1)	0.280^1-151
Sex^1-150
Male	44	11 (34.4%)	17 (56.7%)	16 (40.0%)	0.210^1-152
Female	57	20 (65.6%)	13 (43.3%)	24 (60.0%)
Type
Adenocarcinoma	79	15 (46.9%)	27 (90.0%)	37 (92.5%)	<0.0001^1-152
Mucinous	23	17 (53.1%)	3 (10.0%)	3 (7.5%)
Site^1-160
Right colon	49	28 (87.5%)	7 (24.1%)	14 (35.0%)	<0.0001^1-152
Left colon	28	3 (9.4%)	10 (34.5%)	14 (35.0%)
Rectum	25	1 (3.1%)	12 (41.4%)	12 (30.0%)
Differentiation
Well	5	2 (6.3%)	1 (3.3%)	2 (5.0%)	0.002^1-152
Moderate	66	12 (37.5%)	25 (83.3%)	29 (72.5%)
Poor	31	18 (56.3%)	4 (13.3%)	9 (22.5%)
Duke's stage^1-165
A	15	6 (19.4%)	4 (13.3%)	5 (12.5%)	0.071^1-152
B	51	18 (58.1%)	14 (46.7%)	19 (47.5%)
C	20	5 (16.1%)	3 (10.0%)	12 (30.0%)
D	16	2 (6.5%)	9 (30.0%)	4 (10.0%)

↵1-151 Kruskal-Wallis test.
↵1-152 χ² test.
↵1-150 One MSI-H female patient had two metachronous tumours and therefore is included only once for the sex comparison.
↵1-160 One MSI-L site not available.
↵1-165 One MSI-H stage not available.