Organ failure scores. Each organ failure was scored 0–4 as defined by Bernard and colleagues.28 The score for each patient was the sum of the scores for each organ/system
| Clinically significant organ dysfunction | |||||
|---|---|---|---|---|---|
| Score | 0 Normal | 1 Mild | 2 Moderate | 3 Severe | 4 Extreme |
| Cardiovascular | |||||
| SBP (mm Hg) | >90 | ⩽90 fluid responsive | ⩽90 Not fluid responsive | ⩽90 pH⩽7.3 | ⩽90 pH⩽7.2 |
| Pulmonary | |||||
| PaO2/FiO2 (mm Hg) | >400 | 400–301 | 300–201 acute lung injury | 200–101 ARDS | ⩽100 severe ARDS |
| CNS | |||||
| Glasgow coma score | 15 | 14–13 | 12–10 | 9–6 | ⩾5 |
| Coagulation | |||||
| Platelets (×109/1) | >120 | 120–81 | 80–51 | 50–21 | ⩾20 |
| Renal | |||||
| Creatinine (μmol/1) | ⩽133 | >133 to ⩽169 | >169 to ⩽310 | >310 to ⩽440 | >440 |
SPB, systolic blood pressure; PaO2, arterial oxygen tension; FiO2, inspired oxygen concentration (fraction); ARDS, adult respiratory distress syndrome; CNS, central nervous system.