Plasma levels of glutathione (GSH, its redox state, and its oxidised form (GSSG)) in control, pair fed (PF), pair fed sham operated (PF SO), and cirrhotic (CBDL) rats. No SO data are reported (see text for details).
| Control (n=17) | PF (n=7) | PF SO (n=7) | CBDL (n=11) | ||
| Total GSH (μM) | 9.52 (1.09) | 11.52 (1.98) | 10.04 (1.82) | 4.22 (0.54) | <0.005 |
| GSSG (μM) | 2.42 (0.38) | 2.04 (0.36) | 2.53 (0.48) | 0.76 (0.16) | ns |
| Reduced GSH (μM) | 7.10 (1.07) | 9.48 (1.77) | 7.52 (1.66) | 3.48 (0.47) | <0.005 |
| GSH redox state (GSSG/GSH) | 0.26 (0.04) | 0.19 (0.03) | 0.27 (0.04) | 0.22 (0.05) | ns |
Data are mean (SEM).
Significance values represent differences between the CBDL group and the three control groups (control, PF, and PF SO).