Characteristics of patients with or without factor V Leiden mutation
| With factor (n=20) | Without factor (n=43) | p | |
| Mean (SD) age (y) | 37 (11) | 35 ( 12) | NS |
| Sex ratio (M/F) | 5/15 | 10/33 | NS |
| OC users/child bearing aged women | 4/15 | 19/32 | NS |
| Heavy smoker (n%) | 6 (30) | 14 (43) | NS |
| Prothrombotic states (total No found/total No tested) | 38/94 | 44/239 | 0.00001 |
| Prothrombotic states, excluding factor V Leiden (total No found/total No tested) | 18/74 | 44/239 | NS |
| At least 2 prothrombotic states (n (%)) | 14 (70) | 6 (14) | < 0.005 |
| Isolated antithrombin deficiency2-150 | 0/15 | 0/32 | NS |
| Isolated protein C deficiency2-150 | 1/9 | 3/13 | NS |
| Isolated protein S deficiency2-150 | 1/13 | 1/17 | NS |
| G20210A prothrombin gene transition (No found/No tested)2-160 | 2/15 | 1/32 | NS |
| Primary myeloproliferative disorder (No found/No tested) | 6/18 | 26/43 | NS |
| Acute ischaemic necrosis (ALT >5 ULN) (n (%)) | 6 (30) | 22 (51) | NS |
| Massive ischaemic necrosis (ALT >50 ULN) (n (%)) | 5 (25) | 2 (4.6) | 0.017 |
| Ascites (n (%)) | 17 (85) | 35 (81) | NS |
| Inferior vena cava thrombosis (n (%)) | 8 (40) | 3 (7) | 0.0013 |
| Portal vein thrombosis (n (%)) | 2 (10) | 11 (25) | NS |