Table 1

Patients and pathohistological data

No of patients1 y survival rate (%) (95% CI)Median (95% CI) survival (days)OR (crude)
All4131 (17–45)210 (156–264)
Stage1-c
 Stage I1/41 (5%)100Patient alive (after 1596 days) 1-a
 Stage II7/41 (15%)1007 patients alive (after 257–1323 days)
 Stage IIIA21/41 (51%)24 (0–44)210 (134–286)
 Stage IIIB3/41 (7%)080 (48–112)
 Stage IVA9/41 (22%)089 (0–47)
pT category1-c
 pT1/28/41 (20%)100All alive
 pT3/433/41 (80%)15 (3–27)159 (111–107) 1-a
pN category1-c
 pNO32/41 (78%)40251 (215–287)
 pN19/41 (22%)080 (56–104)8.4 (3.4–20.4)
Grading1-d
 G114/41 (34%)48 (21–75)369
 G221/41 (51%)20 (4–36)156 (71–241)2.8 (1.2–6.5)
 G36/41 (15%)17 (0–47)80 (0–174)3.7 (1.3–11.9)
K-rasmutation
 Yes22/41 (54%)24 (17–42)215 (145–261)
 No19/41 (46%)41 (32–69)291 (156–299)2.0 (1.2–3.2)
p16 methylation
 Yes34/41 (83%)28 (15–43)205 (123–269)
 No7/41 (17%)41 (16–45)235 (171–261)NS
  • 1-a Calculation not possible (insufficient number of patients within the category).

  • 1-b NS, not significant.

  • 1-c Acoording to UICC 1997.14

  • 1-d According to WHO 1994.13