Characteristics of the five epitopes identified
| Epitope | Protein | Presented by | Sequence | Recognised | tTG dependence | Reference |
|---|---|---|---|---|---|---|
| DQ2-γ-I- gliadin | γ gliadin | DQ2 | QPQQSFPQQQ | Infrequently | Total | Sjöströmet al 20 |
| DQ2-α-I-gliadin | α gliadin | DQ2 | QPFPQPQLPY | Frequently | Total | Arentz-Hansenet al 24 |
| DQ2-α-II-gliadin | α gliadin | DQ2 | PQPQLPYPQPQ | Frequently | Total | Arentz-Hansenet al 24 |
| DQ8-α-I-gliadin | α gliadin | DQ8 | SGQGSFQPSQQN | Frequently? | Great | van de Wal et al 21 |
| DQ8-HMW-I-glutenin | HMW glutenin | DQ8 | QGYYPTSPQQS | Not known | None | van de Wal et al 22 |
HWM, high molecular weight; tTG, tissue transglutaminase.
Glutamine (Q) residues that are targeted by tTG and which are important for T cell recognition are indicated in bold.