Presentation at diagnosis of low grade localised gastric mucosa associated lymphoid tissue (MALT) lymphomas according to their Helicobacter pylori status and relationship between clinical and gastric endoscopic ultrasonography (EUS) features and outcome after anti-H pylori eradication, for 19 patients who experienced complete macroscopic and histological remission (responders) and 15 who did not (non-responders). No H pylori negative patient had regression of lymphoma after anti-H pylori treatment.
| H pylori positive patients1-150 | ||||||
|---|---|---|---|---|---|---|
| All Hp+ patients | Responders | Non-responders | Bivariate analysis p1-152 | Multivariate analysis p | H pylori negative patients1-150 | |
| No of cases | 34 | 19 (56%) | 15 | 10 | ||
| Age (y) (mean, range) | 56 (21–76) | 54 (21–76) | 59 (43–73) | 0.0071-151 | NS | 60 (43–76) |
| Sex (M/F) | 22/12 | 10/9 | 12/3 | 0.10 | NS | 7/3 |
| Endoscopy: main features (n) | ||||||
| Ulcer | 25 | 14 | 11 | NS | NS | 6 |
| Erosions | 3 | 1 | 2 | NS | NS | 3 |
| Erythema | 4 | 3 | 1 | NS | NS | 0 |
| Thick folds or tumour | 7 | 2 | 5 | 0.10 | NS | 2 |
| EUS (n): layer infiltrated to: | ||||||
| ⩽Mucosa | 18 | 14 | 4 | <0.0061-164 | NS | 2 |
| Submucosa | 7 | 3 | 4 | 2 | ||
| Muscularis propria | 5 | 1 | 4 | 3 | ||
| Serosa | 4 | 1 | 3 | 3 | ||
| Nodal involvement | 10 | 0 | 10 | <0.0001 | 0.0001 | 5 |
| Adjacent organ | 0 | 0 | 0 | 0 | ||
| Depth of infiltration (mm) (mean (SD)) | 7.6 (5.2) | 5.9 (2.6) | 9.8 (6.9) | 0.005 | NS | 11.1 (5.1) |
| Stage (Ann Arbor) | ||||||
| IE (n) | 24 | 19 (79%) | 5 | 6 | ||
| IIE(n) | 10 | 0 | 10 | 4 | ||