Summary of estimated cancer risks
| Unstratified data | Stratified data | |||||||
|---|---|---|---|---|---|---|---|---|
| All patients (116 studies) | Total UC (35 studies) | All patients (41 studies) | Total UC (26 studies) | Children (5 studies) | All patients (19 studies) | Total UC (6 studies) | ||
| Overall cancer prevalence (%) | 3.7 | 5.4 | ||||||
| (3.2–4.2) | (4.4–6.5) | |||||||
| Cancer incidence rate at 10 years/1000 pyd | 3/1000 | 4/1000 | 6/1000 | 2/1000 | 2/1000 | |||
| (2 to 4/1000) | (3 to 6/1000) | (3 to 13/1000) | (1 to 2 /1000) | (1 to 4/1000) | ||||
| Cumulative cancer risk (%) at 10 years | 3 | 4.4 | 5.5 | 1.6 | 2.1 | |||
| (2.2–3.8) | (2.0–6.8) | (2.5–12.3) | (1.2–2) | (1.0–3.2) | ||||
| Cancer incidence rate at 20 years/1000 pyd | 3/1000 | 4/1000 | 6/1000 | 7/1000 | 7/1000 | |||
| (2 to 4/1000) | (3 to 6/1000) | (3 to 13/1000) | (4 to12 /1000) | (3 to 14/1000) | ||||
| Cumulative cancer risk (%) at 20 years | 5.9 | 8.6 | 10.8 | 8.3 | 8.5 | |||
| (4.3–7.4) | (4.0–13.3) | (4.8–23.1) | (4.8–11.7) | (3.8–13.3) | ||||
| Cancer incidence rate at 30 years/1000 pyd | 3/1000 | 4/1000 | 6/1000 | 12/1000 | 11/1000 | |||
| (2 to 4/1000) | (3 to 6/1000) | (3 to 13/1000) | (7 to19 /1000) | (4 to 28/1000) | ||||
| Cumulative cancer risk (%) at 30 years | 8.7 | 12.7 | 15.7 | 18.4 | 17.8 | |||
| (6.4–10.9) | (6.0–19.3) | (7.2–32.6) | (15.3–21.5) | (8.3–27.4) | ||||
Values are mean (95% confidence intervals).
pyd, person years duration.