Table 3

Sensitivity, specificity, and positive and negative predictive values per biopsies for detection of dysplastic lesions in Barrett's oesophagus after different sensitisations using 5-aminolaevulinic acid (5-ALA)

5-ALA application mode Examinations (biopsies) (n) Sensitivity (%) Specificity (%) Pos. predictive value (%) Neg. predictive value (%)
500 mg locally22  (96)60691894
5 mg/kg orally4 (20)700100
10 mg/kg orally13 (56)80564088
20 mg/kg orally13 (44)1005113100
30 mg/kg orally6 (27)1002723100