Table 1

Glypican-3 mRNA expression in patients with hepatocellular carcinoma

Patient No Age (y) Sex Stage1-a Grade1-b Pushing/ invading1-c Relative optical density1-d (northern blot analysis)
166MII2P8.8
257MII3P5.9
333MIII2P5.0
454FIII1I1.4
576MIII1I1.5
661MIII2P5.6
763FIII3P10.2
878MIII3I5.5
976MIII2I0.2
1071FIII2P5.9
1162MIII2P13.9
1263MIII2I4.8
1363MIII2P14.6
1475MIII2P4.3
1564MIII3P3.3
1660MIII2P0.0
1764MIV3P0.3
1854MIV4I3.8
1969FIV2I0.0
2066MIV2P1.6
2161FIV3P1.5
2265MIV3I0.1
2356MIV3I10.1
2473MIV1I2.8
2567FIV3P17.5
2668MIV2P4.9
2764FIV2I1.9
2838FIV3P18.5
2965FIV3P20.5
3052FIV1P20.4
  • 1-a No significant difference between stages III and IV (p>0.05);

  • 1-b no significant difference between grades 1+2 and grades 3+4 (p>0.05);

  • 1-c significant difference between pushing (P) and invading (I) groups (p<0.05);

  • 1-d ratio of optical density of glypican-3/optical density of 7S.