Table 2

Duodenal damage scores (modified Lanza score): comparison of treatment effects of nimesulide and naproxen, and comparison of responders (Lanza score 0, 1) and non-responders (Lanza score >1)

Nimesulide
Lanza score2-15001234Total naproxen
Naproxen
 015310120  (57%)
 1 300004 (11%)
 2 611007 (20%)
 3 300003 (9%)
 4 100001 (3%)
Total nimesulide (%)28 (80%)4 (11%)2 (6%)0 (0%)1 (3%)35
Analysis of responders2-151
Nimesulide
Responder (0, 1) Non-responder (2, 3, 4)
Naproxen
 Responder222
 Non-responder101
  • McNemar test: p<0.001 (two sided).

  • 2-150 Modified Lanza score: 0, normal; 1, erosion or submucosal haemorrhage; 2, 2–10 erosions or submucosal haemorrhages; 3, >10 erosions or submucosal haemorrhage; 4, ulcer.

  • 2-151 Responder is a Lanza score of 0 or 1; a non-responder is a Lanza score of >1.