Multivariate analysis of predictors of fibrosis stages 3 and 4 at initial biopsy
| Factor | Odds ratio | 95% CI |
| Age at biopsy (y) | ||
| <30 | Ref | |
| 30–39 | 11.1 | 1.2–106 |
| 40–49 | 23.2 | 2.4–224 |
| >50 | 131 | 11.7–1483 |
| Hepatitis B markers | ||
| Anti-HBc neg | Ref | |
| Anti-HBc pos | 3.4 | 1.0–11.1 |
| NI grade | ||
| 0–4 | Ref | |
| 5–8 | 7.6 | 2.9–20 |
| 9–12 | 43 | 10.3–184 |
| 13–18 | 82 | 2.4–2770 |
NI, necroinflammatory; anti-HBc, antibody to hepatitis B core antigen.